Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Very clear+ tissue clearing approach is the sole method that delipidates samples with no change in morphology and with minimal influence on structural integrity.
Megatome is usually a vibrating microtome built to part a wide array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome permits substantial-throughput tissue sectioning with uniform surface area profile, along with minimal tissue harm and information decline.
Antibodies may possibly consider months to diffuse by way of only a few millimeters of tissue, that has a steep labeling gradient from surface area to Main.
Megatome is created for accuracy: the blade vibrates at the next frequency and larger amplitude range than other microtomes, and encompasses a exclusive deflection Manage system.
SE employs a rotational electric discipline to disperse extremely electromobile molecules (for instance antibodies or surfactant micelles) all through a porous sample without the need of detrimental electrically charged constructions throughout the tissue. This enables two-4 day clearing of intact organs,
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Megatome is a novel microtome that allows for high-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with nominal tissue megatomi.com hurt and knowledge decline.
eFLASH is usually a rapid tissue labeling technique that allows for uniform entire-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope supplies unparalleled resolution and acquisition pace during intact tissue volumes, whilst its modular style permits you to improve and customize person components.
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SHIELD avoids the variability of hydrogel embedding and the data reduction from PFA preservation, defending specimens for multiple rounds of processing.
Leverage the Crystal clear+ tissue clearing approach, along with eFLASH and patented stochastic electrotransport systems, to speedily distinct and label full organs. Essential highlights and features incorporate:
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